UPSC Medical Science Optional Syllabus

UPSC Optional Syllabus for Medical Science- Paper I 

  1. Human Anatomy:
  • Applied anatomy including blood and nerve supply of upper and lower limbs and joints of shoulder, hip and knee.
  • Gross anatomy, blood supply and lymphatic drainage of tongue, thyroid, mammary gland, stomach, liver, prostate, gonads and uterus
  • Applied anatomy of diaphragm, perineum and inguinal region.
  • Clinical anatomy of kidney, urinary bladder, uterine tubes, vas deferens.
  • Embryology: Placenta and placental barrier. Development of heart, gut, kidney, uterus, ovary, testis and their common congenital abnormalities.
  • Central and peripheral autonomic nervous system: Gross and clinical anatomy of ventricles of brain, circulation of cerebrospinal fluid; Neural pathways and lesions of cutaneous sensations, hearing and vision; Cranial nerves, distribution and clinical significance; Components of autonomic nervous system.
  1. Human Physiology:
  • Conduction and transmission of impulse, mechanism of contraction, neuromuscular transmission, reflexes, control of equilibrium, posture and muscle tone, descending pathways, functions of cerebellum, basal ganglia, Physiology of sleep and consciousness.
  • Endocrine system: Mechanism of action of hormones, formation, secretion, transport, metabolism, function and regulation of secretion of pancreas and pituitary gland.
  • Physiology of reproductive system: menstrual cycle, lactation, pregnancy.
  • Blood: Development, regulation and fate of blood cells.
  • Cardio-vascular, cardiac output, blood pressure, regulation of cardiovascular functions;
  1. Biochemistry:
  • Organ function tests-liver, kidney, thyroid
  • Protein synthesis.
  • Vitamins and minerals.
  • Restriction fragment length polymorphism (RFLP).
  • Polymerase chain reaction (PCR).
  • Radio – immunoassays (RIA).
  1. Pathology:
  • Inflammation and repair, disturbances of growth and cancer, Pathogenesis and histopathology of rheumatic and ischemic heart disease and diabetes mellitus. 
  • Differentiation between benign, malignant, primary and metastatic malignancies, Pathogenesis and histopathology of bronchogenic carcinoma, carcinoma breast, oral cancer, cancer cervix, leukemia, Etiology, pathogenesis and histopathology of – cirrhosis liver, glomerulonephritis, tuberculosis, acute osteomyelitis.
  1. Microbiology:
  • Humoral and cell mediated immunity
  • Diseases caused by and laboratory diagnosis of
  • Meningococcus, Salmonella
  • Shigella, Herpes, Dengue, Polio
  • HIV/AIDS, Malaria, E. Histolytica, Giardia
  • Candida, Cryptococcus, Aspergillus
  1. Pharmacology:

Mechanism of action and side effects of the following drugs

  • Antipyretics and analgesics, Antibiotics, Antimalaria; Antikala-azar,Antidiabetics
  • Antihypertensive, Antidiuretics, General and cardiac vasodilators, Antiviral, Antiparasitic, Antifungal, Immunosuppressants
  • Anticancer
  1. Forensic Medicine and Toxicology: 
  • Forensic examination of injuries and wounds; 
  • Examination of blood and seminal stains; 
  • poisoning, sedative overdose, hanging, drowning, burns, 
  • DNA and finger print study

UPSC Optional Syllabus for Medical Science- Paper-II 

  1. General Medicine:
  • Etiology, clinical features, diagnosis and principles of management (including prevention) of: – Tetanus, Rabies, AIDS, Dengue, Kala-azar, Japanese Encephalitis.
  • Etiology, clinical features, diagnosis and principles of management of:
  • Ischaemic heart disease, pulmonary embolism.
  • Bronchial asthma.
  • Pleural effusion, tuberculosis, Malabsorption syndromes, acid peptic diseases, Viral hepatitis and cirrhosis of liver.
  • Glomerulonerphritis and pyelonephritis, renal failure, nephrotic syndrome, renovascular hypertension, complications of diabetes mellitus, coagulation disorders, leukemia, Hypo and hyper thyrodism, meningitis and encephalitis.
  • Imaging in medical problems, ultrasound, echocardiogram, CT scan, MRI.
  • Anxiety and Depressive Psychosis and schizophrenia and ECT.
  1. Pediatrics:
  • Immunization, Baby friendly hospital, congenital cyanotic heart disease, respiratory distress syndrome, broncho – pneumonias, kernicterus. 
  • IMNCI classification and management, PEM grading and management.
  •  ARI and Diarrhea of under five and their management.
  1. Dermatology:

Psoriasis, Allergic dermatitis, scabies, eczema, vitiligo, Stevan Johnson’s syndrome, Lichen Planus.

  1. General Surgery:
  • Clinical features, causes, diagnosis and principles of management of cleft palate, harelip.
  • Laryngeal tumor, oral and esophageal tumors.
  • Peripheral arterial diseases, varicose veins, coarctation of aorta
  • Tumors of Thyroid, Adrenal Glands
  • Abscess, cancer, fibroadenoma and adenosis of breast.
  • Bleeding peptic ulcer, tuberculosis of bowel, ulcerative colitis, cancer stomach.
  • Renal mass,cancer Prostate..
  • Haemothorax, stones of Gall bladder, Kidney, Ureter and Urinary Bladder.
  • Management of surgical conditions of Rectum, Anus and Anal canal, Gall bladder and Bile ducts
  • Splenomegaly, cholecystitis, portal hypertension, liver abscess, peritonitis, carcinoma head of pancreas.
  • Fractures of spine, Colles’ fracture and bone tumors.
  • Endoscopy
  • Laprascopic Surgery.
  1. Obstetrics and Gynaecology including Family Planning:
  • Diagnosis of pregnancy.
  • Labour management, complications of 3rd stage, Antepartum and postpartum hemorrhage, resuscitation of the newborn, Management of abnormal lie and difficult labour, Management of small for date or premature newborn.
  • Diagnosis and management of anemia. Preeclampsia and Toxaemias of pregnancy, Management of Post menopausal Syndrome.
  • Intra-uterine devices, pills, tubectomy and vasectomy. Medical termination of pregnancy including legal aspects.
  • Cancer cervix.
  • Leucorrhoea, pelvic pain, infertility, dysfunctional uterine bleeding (DUB), amenorrhoea, Fibroid and prolapse of uterus.
  1. Community Medicine (Preventive and Social Medicine):

Principles, methods, approach and measurements of Epidemiology

  • Nutrition, nutritional diseases / disorders & Nutrition Programmes.
  • Health information Collection, Analysis and Presentation.
  • Objectives, components and critical analysis of National programmes for control/eradication of:
  • Malaria, Kala-azar, Filaria and Tuberculosis,
  • HIV/AIDS, STDs and Dengue
  • Critical appraisal of Health care delivery system.
  • Health management and administration: Techniques, Tools, Programme Implementation and Evaluation.
  • Objective, Component, Goals and Status of Reproductive and Child Health, National Rural Health Mission and Millennium Development Goals
  • Management of hospital and industrial waste.

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